Eat Right, Save Your Eyesight
NEW YORK (Reuters Health) - High dietary levels of omega-3 long-chain polyunsaturated fatty acids and fish may reduce the risk of age-related macular degeneration, new research suggests.
Tuesday, May 15, 2007
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NEW YORK (Reuters Health) - High dietary levels of omega-3 long-chain polyunsaturated fatty acids and fish may reduce the risk of age-related macular degeneration, new research suggests.
The findings are largely supportive of earlier work linking omega-3 long-chain polyunsaturated fatty acids and foods rich in these fatty acids can block or slow age-related macular degeneration, according to a report in the Archives of Ophthalmology.
The research involved an analysis of data for 4,519 subjects who participated in the Age-Related Eye Disease Study (AREDS). A self-administered food frequency questionnaire was used to assess the subjects' diet content in the year prior to study enrollment.
After accounting for overall calories and other variables, those with the highest levels of total omega-3 long-chain polyunsaturated fatty acids in their diet had a 39-percent reduced risk of neovascular age-related macular degeneration compared with those with the lowest dietary levels. The corresponding risk reduction for dietary levels of docosahexaenoic acid, a retinal omega-3 long-chain polyunsaturated fatty acid, was 46 percent, the AREDS Research Group reports.
High levels of fish, in general, and broiled or baked fish cut the risk of neovascular age-related macular degeneration by 39 percent and 35 percent, respectively.
By contrast, intake of arachidonic acid, an omega-6 fatty polyunsaturated acid found in phospholipids, cell membrane and brain, seemed to increase the risk of neovascular age-related macular degeneration. Compared with subjects with the lowest dietary levels, those with the highest levels had a 54-percent increased risk, the investigators found.
These findings and those from other investigations suggest that modifying the diet to include more foods rich in omega-3 long-chain polyunsaturated fatty acids could lead a reduced risk of neovascular age-related macular degeneration, the authors conclude.
SOURCE: Archives of Ophthalmology, May 2007.
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